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500 mg pure β-Nicotinamide Mononucleotide per capsule · 90 Capsules · 45-Day Supply Our highest-potency pure NMN formula designed to support cellular energy, healthy aging, and maximum vitality.
45-Day Supply
cGMP Certified
Third-Party Tested
Made in USA
≥99% Purity NMN
⚡
Cellular Energy
Replenishes NAD+ to fuel mitochondrial energy production and physical endurance.
🧬
DNA Repair
Activates sirtuins and PARP enzymes that maintain genomic integrity and cellular health.
🧠
Cognitive Clarity
Supports brain NAD+ levels to maintain focus, memory, and mental sharpness.
🌿
Healthy Aging
Combats the natural NAD+ decline that accelerates after age 30 to support longevity.
SUPPLEMENT FACTS SNAPSHOT
Serving Size: 2 CapsulesServings Per Container: 45
Ingredient
Per Serving (2 Capsules)
β-Nicotinamide Mononucleotide (NMN)
1000 mg
† Daily Value not established. Other ingredients: Vegetable Cellulose (capsule), Microcrystalline Cellulose, Magnesium Stearate.
Suggested Use
As a dietary supplement, adults take 2 capsules once daily, preferably in the morning on an empty stomach or as directed by a healthcare professional. Take with a full glass of water. For best results, use consistently for a minimum of 8–12 weeks.
* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Consult your healthcare provider before use if you are pregnant, nursing, taking medication, or have a medical condition. Keep out of reach of children. Store in a cool, dry place.
What Is AIDEVI NMN 45000?
AIDEVI NMN 45000 is our highest-potency, pure NAD+ booster supplement, delivering a massive 500 mg of pure β-Nicotinamide Mononucleotide (NMN) per capsule. With 90 capsules per bottle, it provides a total of 45,000 mg of NMN across a full 45-day supply. The "45000" in the product name reflects this total NMN content per bottle, a transparent labelling convention that allows consumers to understand exactly what they are getting.
NMN is a direct precursor to Nicotinamide Adenine Dinucleotide (NAD+), a coenzyme found in every living cell and essential for energy metabolism, DNA repair, and the activation of longevity-linked proteins called sirtuins. Unlike NAD+ itself — which cannot easily cross cell membranes — NMN is actively transported into cells, where it is rapidly converted into NAD+. This makes NMN supplementation one of the most direct and scientifically validated strategies for restoring cellular NAD+ levels.
AIDEVI NMN 45000 is manufactured in a cGMP-certified facility in the United States and independently verified for purity and potency. By focusing exclusively on pure, high-dose NMN, this formula is designed for individuals seeking maximum NAD+ restoration without additional co-ingredients.
The Science Behind NAD+ Decline
NAD+ is arguably one of the most important molecules in the human body. It serves as the central hub of cellular metabolism, acting as an electron carrier in the mitochondrial energy production chain and as a substrate for critical repair enzymes, including PARPs and sirtuins. Research has established that NAD+ levels decline by approximately 50% between the ages of 40 and 60.
NAD+ Level Decline With Age (Relative to Peak at Age 20)
100%
Age 20
~80%
Age 30
~60%
Age 40
~45%
Age 50
~30%
Age 60+
Illustrative representation based on peer-reviewed research on age-related NAD+ decline. Individual results may vary.
This decline is not merely a passive consequence of aging — it is an active driver of it. When NAD+ levels fall, mitochondria become less efficient, DNA repair slows, and the sirtuin proteins that regulate cellular stress responses become less active.
Multiple human clinical studies have confirmed that oral NMN supplementation safely and significantly increases blood NAD+ levels in healthy adults. A randomised, double-blind study demonstrated that NMN doses of 600–1200 mg/day significantly improved aerobic capacity and muscle oxygen utilisation in middle-aged runners.
The Formula: Pure, High-Potency Focus
AIDEVI NMN 45000 is designed for one specific purpose: delivering the highest possible dose of pure NMN in a convenient daily serving.
Star Ingredientβ-Nicotinamide Mononucleotide (NMN) — 1000 mg per serving
At the heart of the formula is ≥99% purity β-NMN, the biologically active form of Nicotinamide Mononucleotide. At 500 mg per capsule (1000 mg per daily serving), AIDEVI NMN 45000 delivers a clinical-strength dose aligned with the highest dosage ranges studied in human trials. Each serving provides the massive influx of NAD+ precursor substrate that cells require to rapidly regenerate this critical coenzyme.
A 2022 study published in Scientific Reports confirmed that oral administration of NMN at doses up to 1250 mg/day is safe, well-tolerated, and results in a dose-dependent increase in blood NAD+ levels.
Clinical trials show high-dose NMN improves aerobic capacity and muscle oxygen utilisation. Ideal for boosting physical performance and recovery.
🧠 Professionals
For individuals experiencing brain fog. NMN supports brain NAD+ levels, critical for neuronal health, memory retention, and mental clarity.
⏳ Anti-Aging Advocates
For adults over 40 aggressively combating the 50% decline in NAD+ levels. Provides robust cellular support to activate sirtuins and vitality.
🎯 Custom Stackers
For biohackers who build their own stacks. Pure NMN without co-ingredients allows precise control of NAD+ precursor intake.
The AIDEVI Quality Standard
As the Nutraceutical Brand of the Year (Corporate LiveWire Global Awards 2025/26), AIDEVI is committed to uncompromising quality, transparency, and safety.
cGMP Certified
Strict compliance with FDA standards.
Third-Party Tested
≥99% NMN purity verified.
Non-GMO & Vegan
No fillers, dairy, or gluten.
Made in USA
Proudly manufactured in America.
Frequently Asked Questions
What does "NMN 45000" mean?
The number 45000 refers to the total milligrams of NMN contained in one bottle. Each bottle contains 90 capsules, and each capsule provides a potent 500 mg dose of high-purity NMN (500 mg × 90 capsules = 45,000 mg total).
Is a 1000 mg daily dose of NMN safe?
Yes. Multiple human clinical trials have demonstrated that NMN is safe and well-tolerated at high doses. A 2022 study confirmed the safety of oral NMN administration at doses up to 1250 mg per day for 4 weeks.
When is the best time to take NMN 45000?
We recommend taking your daily serving (2 capsules) in the morning on an empty stomach. This aligns with your natural circadian rhythm and provides sustained energy throughout the day without interfering with sleep.
How does NMN 45000 compare to other versions?
AIDEVI NMN 45000 is our highest-potency, pure NMN formula (1000 mg/day). NMN 18000 provides 300 mg alongside Resveratrol and TMG, while NMN 21000 is a 9-in-1 formula (600 mg). Choose NMN 45000 for the maximum dose of pure NMN.
How long does it take to see results?
NMN begins elevating blood NAD+ levels quickly. Noticeable physical benefits (energy, mental clarity) typically take 2–4 weeks. For deeper cellular benefits, consistent daily use for 8–12 weeks is optimal.
Should I take TMG with this supplement?
Many experts recommend pairing high-dose NMN with a methyl donor like TMG (Trimethylglycine) to support healthy methylation pathways. You can easily stack NMN 45000 with a separate TMG supplement.
Scientific References
Liao, B., et al. (2021). Nicotinamide mononucleotide supplementation enhances aerobic capacity in amateur runners: a randomized, double-blind study. Journal of the International Society of Sports Nutrition, 18(1), 54. https://pmc.ncbi.nlm.nih.gov/articles/PMC8265078/
Fukamizu, Y., et al. (2022). Safety evaluation of β-nicotinamide mononucleotide oral administration in healthy adult men and women. Scientific Reports, 12(1), 14442. https://pmc.ncbi.nlm.nih.gov/articles/PMC9400576/
Zhao, Y., et al. (2020). Nicotinamide Mononucleotide Administration Prevents Experimental Diabetes-Induced Cognitive Impairment and Loss of Hippocampal Neurons. International Journal of Molecular Sciences, 21(11), 3756. https://pmc.ncbi.nlm.nih.gov/articles/PMC7313029/
Nadeeshani, H., et al. (2021). Nicotinamide mononucleotide (NMN) as an anti-aging health product - Promises and safety concerns. Journal of Advanced Research, 37, 267–278. https://pmc.ncbi.nlm.nih.gov/articles/PMC9039735/
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