What Is AIDEVI NMN 18000?
AIDEVI NMN 18000 is a premium NAD+ booster supplement delivering 300 mg of pure β-Nicotinamide Mononucleotide (NMN) per capsule — 60 capsules per bottle, totalling 18,000 mg of NMN across the full supply. The "18000" in the product name reflects this total NMN content per bottle, a transparent labelling convention that allows consumers to make direct, apples-to-apples comparisons across brands.
NMN is a direct precursor to Nicotinamide Adenine Dinucleotide (NAD+), a coenzyme found in every living cell and essential for energy metabolism, DNA repair, and the activation of longevity-linked proteins called sirtuins. Unlike NAD+ itself — which cannot cross cell membranes — NMN is actively transported into cells via a dedicated transporter protein (Slc12a8), where it is rapidly converted into NAD+. This makes NMN supplementation one of the most direct and scientifically validated strategies for restoring cellular NAD+ levels.
AIDEVI NMN 18000 is manufactured in a cGMP-certified facility in the United States, independently verified for purity and potency, and formulated with a synergistic blend of Trans-Resveratrol, Trimethylglycine (TMG), and BioPerine® to maximise bioavailability and efficacy.
The Science Behind NAD+ Decline
NAD+ is arguably one of the most important molecules in the human body. It serves as the central hub of cellular metabolism, acting as an electron carrier in the mitochondrial energy production chain and as a substrate for critical repair enzymes, including PARPs (Poly ADP-Ribose Polymerases) and sirtuins. Research published in Cell Metabolism and Nature Reviews Molecular Cell Biology has established that NAD+ levels decline by approximately 50% between the ages of 40 and 60.
NAD+ Level Decline With Age (Relative to Peak at Age 20)
Illustrative representation based on peer-reviewed research on age-related NAD+ decline. Individual results may vary.
Pioneering research from institutions including Harvard Medical School's Sinclair Lab has demonstrated that restoring NAD+ levels through NMN supplementation can reverse many cellular aging markers. Multiple human clinical trials have confirmed that oral NMN safely and significantly increases blood NAD+ levels in healthy middle-aged adults.
The AIDEVI Formula: Ingredient Synergy
Unlike single-ingredient NMN products, AIDEVI NMN 18000 is formulated as a synergistic longevity complex. Each co-ingredient was selected based on peer-reviewed evidence to amplify NMN's core mechanisms.
STAR INGREDIENT β-Nicotinamide Mononucleotide (NMN) — 300 mg per capsule
At the heart of the formula is ≥99% purity β-NMN, delivering a clinically relevant dose aligned with ranges studied in human trials. Each capsule provides the NAD+ precursor substrate that cells require to regenerate this critical coenzyme.
A 2024 study published in Nutrients demonstrated that NMN intake maintained walking speed and improved sleep quality in older adults — confirming functional benefits beyond simple biomarker improvements.
Trans-Resveratrol — 30 mg per capsule
Trans-Resveratrol is a naturally occurring polyphenol and a well-studied activator of SIRT1. The combination of NMN and Resveratrol creates a powerful synergy: NMN provides the NAD+ substrate, while Resveratrol activates SIRT1's deacetylase activity, maximizing the cellular health benefits.
Trimethylglycine (TMG / Betaine) — 60 mg per capsule
TMG addresses a key biochemical consideration in NMN supplementation. As NMN is converted to NAD+, it generates nicotinamide, which is methylated and excreted. TMG donates methyl groups to replenish this pool, ensuring the body's methylation cycle remains uninterrupted for long-term safety.
BioPerine® (Black Pepper Extract) — 5 mg per capsule
BioPerine® is clinically demonstrated to enhance the bioavailability of co-administered nutrients by up to 20%. Its inclusion ensures that the active ingredients in each capsule are absorbed more efficiently, maximising the return on every dose.
Evidence-Informed Benefits
| Benefit Area |
Mechanism |
Supporting Evidence |
| Cellular Energy |
NMN restores NAD+ levels in mitochondria, enhancing the efficiency of ATP synthesis. |
Nadeeshani et al., 2022 |
| DNA Repair |
NAD+ acts as the substrate for PARP enzymes that repair DNA strand breaks. |
PMC Review, 2024 |
| Cognitive Function |
Supports neuronal energy metabolism and protects against oxidative stress in the brain. |
Sinclair Lab, Harvard |
| Physical Recovery |
Improves muscle cell energy production and reduces post-exercise oxidative damage. |
Morifuji et al., 2024 |
* These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.