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Premium Quality | Lab-Verified
Experience the difference with our clinically-studied, high-purity ingredients. Every batch is rigorously third-party lab tested for potency, purity (99%+), and safety, ensuring you get the premium quality you deserve.
Formulated with high-purity NR, L-Ergothioneine (EGT), PQQ, Pterostilbene, and Spermidine to directly boost NAD+ levels, enhance mitochondrial health, and activate cellular renewal.
30-Day Supply
cGMP Certified
Third-Party Tested
Made in USA
Enteric-Coated
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NAD+ Boost
Replenishes declining NAD+ levels with Nicotinamide Riboside (NR) to support cellular energy production and DNA repair.
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Mitochondrial Health
Promotes mitochondrial biogenesis and enhances cellular energy capacity with PQQ and the "longevity vitamin" EGT.
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Cellular Cleanup
Activates autophagy with Spermidine to remove damaged cells, clear cellular debris, and promote healthy cellular renewal.
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Cognitive & Aging Support
Provides robust antioxidant protection and sirtuin activation via Pterostilbene to support brain health and longevity pathways.
SUPPLEMENT FACTS SNAPSHOT
Serving Size: 2 Capsules Servings Per Container: 30
Ingredient
Per Serving (2 Caps)
Nicotinamide Riboside (NR)
*
L-Ergothioneine (EGT)
*
Pyrroloquinoline Quinone (PQQ)
*
Pterostilbene
*
Spermidine (SPD)
*
* Daily Value not established. Other ingredients: Enteric-Coated Capsule.
📋 Suggested Use
As a dietary supplement, adults take two (2) capsules daily with water, preferably with a meal, or as directed by your healthcare professional. The advanced enteric-coated capsule design ensures the active ingredients survive stomach acid for maximum bioavailability and absorption in the gut. For optimal results, maintain consistent daily intake.
* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary. Always consult with a healthcare professional before starting any new supplement regimen, especially if you are pregnant, nursing, taking medications, or have pre-existing health conditions. Keep out of reach of children. Store in a cool, dry place away from direct sunlight.
What Is AIDEVI NAD+ SUSTAIN?
AIDEVI NAD+ SUSTAIN is a revolutionary, multi-targeted cellular longevity supplement designed to address the core mechanisms of aging. At its foundation is a highly efficient NAD+ precursor, Nicotinamide Riboside (NR), which directly replenishes declining NAD+ levels to restore cellular energy and vitality.
Unlike single-ingredient NAD+ boosters, NAD+ SUSTAIN features a comprehensive 5-in-1 synergistic formula. It combines NR with four other scientifically backed compounds: L-Ergothioneine (EGT), Pyrroloquinoline Quinone (PQQ), Pterostilbene, and Spermidine. Together, these ingredients protect mitochondria from oxidative stress, stimulate new mitochondrial growth, and activate cellular autophagy.
Manufactured in a cGMP-certified facility in the United States, utilizing advanced enteric-coated capsules for maximal small intestine absorption.
The Science of Cellular Aging
As we age, NAD+ levels naturally decline by approximately 50% between the ages of 40 and 60, impairing energy metabolism and DNA repair.
The Three Pillars of Cellular Decline
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NAD+ Depletion
Impairs energy metabolism and reduces the activity of sirtuins, leading to less efficient DNA repair.
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Mitochondrial Decline
Mitochondrial function drops and numbers decrease, causing fatigue and increased oxidative stress.
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Autophagy Impairment
The cellular "self-eating" process slows down, leading to the accumulation of toxic cellular debris.
Formula Deep-Dive: A 5-in-1 Masterpiece
The true power lies in the synergistic interaction of five key ingredients ensuring cellular machinery is protected, repaired, and optimized.
STAR INGREDIENTNicotinamide Riboside (NR)
Mechanism: NR is a highly efficient precursor to NAD+. It easily crosses cell membranes and rapidly converts into NAD+, fueling mitochondrial function and activating sirtuins.
L-Ergothioneine (EGT)
Mechanism: The "longevity vitamin" enters cells directly to safeguard mitochondrial DNA and proteins from oxidative damage.
PQQ (Pyrroloquinoline Quinone)
Mechanism: Stimulates mitochondrial biogenesis (growth of new mitochondria) and defends neurons against oxidative stress.
Pterostilbene
Mechanism: Similar to resveratrol but with 4x better bioavailability. Works synergistically with NAD+ to activate sirtuins for DNA repair.
Spermidine (SPD)
Mechanism: A potent inducer of autophagy, clearing out old cellular components to make way for healthy, new cells.
Evidence-Informed Benefits
Benefit Area
Mechanism of Action
Supporting Evidence
NAD+ Boost & DNA Repair
NR efficiently replenishes NAD+ levels, providing substrate for sirtuin-mediated DNA repair.
* These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.
Who Is It Designed For?
Adults 40+ Experiencing Energy Decline
Restores the cellular energy needed to combat persistent fatigue and maintain an active lifestyle as natural NAD+ levels drop.
Professionals Seeking Cognitive Clarity
Supports mitochondrial function in the brain and provides neuroprotection to maintain sharp focus during high-stress work.
Women Navigating Hormonal Changes
Provides critical support against accelerated cellular stress during hormonal transitions via autophagy induction.
Proactive Longevity Enthusiasts
A convenient, synergistic 5-in-1 stack for those already optimizing their lifespan and healthspan protocols.
The AIDEVI Quality Standard
Awarded "Nutraceutical Brand of the Year" — Uncompromising standards for purity and efficacy.
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cGMP Certified
Strict FDA Current Good Manufacturing Practice.
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Third-Party Tested
Independently verified for 99%+ purity & potency.
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Natural Formula
Clean ingredients without harmful additives.
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Made in USA
Produced in Rancho Cucamonga, California.
Frequently Asked Questions
What is NAD+ and why does it decline with age?
NAD+ is a vital coenzyme found in every cell. As we age, our bodies produce less and consume more to repair damage, resulting in up to a 50% decline by middle age, leading to fatigue and health issues.
Nicotinamide Riboside (NR) vs NMN: Which is better?
Both are highly effective. NR is a smaller molecule that enters cells easily before converting to NAD+. AIDEVI NAD+ SUSTAIN uses NR for maximum efficiency, while our AIDEVI NMN 18000 uses NMN.
Why Pterostilbene instead of Resveratrol?
Studies show Pterostilbene has approx. 4x better absorption and a 5x longer half-life than resveratrol, providing sustained antioxidant protection.
How long does it take to see results?
Many report increased energy in 2-4 weeks. However, deeper cellular benefits (mitochondrial function, DNA repair) are cumulative. We recommend consistent use for 3-6 months.
Why are enteric-coated capsules important?
NAD+ precursors can degrade in stomach acid. Enteric coating ensures the capsule dissolves in the alkaline small intestine, maximizing absorption of active ingredients.
Scientific References
Dellinger RW, et al. "Repeat dose NRPT (nicotinamide riboside and pterostilbene) increases NAD+ levels in humans safely and sustainably: a randomized, double-blind, placebo-controlled study." npj Aging and Mechanisms of Disease. 2017. Nature
Martens CR, et al. "Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD+ in healthy middle-aged and older adults." Nature Communications. 2018. Nature
Sharma A, et al. "Potential synergistic supplementation of NAD+ promoting compounds as a strategy for increasing healthspan." Nutrients. 2023. MDPI
Madeo F, et al. "Spermidine: a physiological autophagy inducer acting as an anti-aging vitamin in humans?" Autophagy. 2019. PMC6287690
Chowanadisai W, et al. "Pyrroloquinoline quinone stimulates mitochondrial biogenesis through cAMP response element-binding protein phosphorylation and increased PGC-1alpha expression." Journal of Biological Chemistry. 2010. PMC2804159
Tian X, et al. "Ergothioneine: an underrecognised dietary micronutrient required for healthy ageing." British Journal of Nutrition. 2023. PMC9816654